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PWR - Belimumab: A New Treatment Option for Lupus Nephritis in British Columbia

  • Dr. Sinead Stoneman and Dr. Sean Barbour
Learning Objectives:
  1. Review the pharmacology and mechanism of action of belimumab, as well as its immunologic and clinical rationale in lupus nephritis.
  2. Critically appraise the evidence base for belimumab in lupus nephritis, with emphasis on trial design, endpoints, efficacy and safety, subgroup analyses, and long-term kidney outcomes.
  3. Identify practical considerations for incorporating belimumab into clinical practice in BC.
  4. Review the logistics for funding belimumab for lupus nephritis through the BC Renal GN formulary, as of June 1 2025.

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